iris publishers | Universidad Nacional Autónoma de México

Microbiota of the Gut: Antibiotic-Induced Dysbiosis and the Adverse Effects on Human Health
Iris Publishers LLC, 2018
A healthy gut microbial community is essential for homeostasis in mammals. A symbiotic relationship between host and microbe s essential in developing the immune system, providing biomolecules and generating energy through utilisation of indigestible
compounds. The diversity of the gut microbiota is altered following antibiotic treatments, the effect this has on the health and
wellbeing of the host has long been underestimated and is now the subject of intense debate. Antibiotics facilitate the selection of
energy harvesting microbes within the gut and hence heavily influence the gaining of weight and may be contributing more than we
anticipated to the modern obesity epidemic. These changes to the bacterial composition of the gut, dysbiosis are caused by elevated
oxygen levels within the gut that promotes the propagation of facultative anaerobic Proteobacteria, a condition associated with
inflammation and cancer. Additionally, the altered oxygenated intestinal climate allows the growth of aerobic pathogens, conveying
clinically relevant resistance genes on highly transmissible mobile elements between communities or acquiring them from
commensal bacteria, in turn aiding the spread of antibiotic resistance. Here we discuss the indirect pleotropic effects antibiotics
have on the microbial community and environment of the gut leading to hidden adverse implications to human health.

https://unam.academia.edu/irispublishers

Comments

Post a Comment

Popular posts from this blog

Gully Erosion and Landslides in Southeastern Nigeria: Causes, Consequences and Control Measures

Image
  Abstract In southeastern Nigeria, soil and gully erosion and landslides are responsible for the widespread destructions of human, animal and plant lives, domestic, industrial and commercial property, transportation and communication systems, degradation of arable lands, contamination of surface and groundwater supplies, isolation of settlements and migration of communities. This account presents some of the results of research and studies of gully erosion and landslides carried out over the years in parts of southeastern States of Abia, Anambra, Enugu, Ebonyi and Imo States. Gully erosion is attributed to natural and anthropogenic causes, with the latter being most prevalent. Gully initiation is the result of localized erosion by surface runoff and soil eluviation associated with rainfall events of high intensity. Erosion is frequently concentrated where the forest cover has been removed for agricultural, urbanization and construction purposes and also at sites of u...
Read more

Iris Publishers

  Biological Processes In Urban Mines Authored by Navarro Hidalgo Keywords: Critical elements; Microorganisms; Urban mines; Biological processes; Recycling Introduction The innovation and development of high technology have demanded the exploration of some chemical elements in greater quantity. These elements have physicochemical properties of high economic interest. Some countries have larger amounts of the reserves of these elements, creating an imbalance in world supply. An example of the use of these materials are rare earth elements widely used in equipment with greater energy efficiency and magnets in wind generators. They are also present in increasingly modern computers, cell phones and televisions. Given this reality, thiswork proposes to recover critical elements from alternative sources (electronic waste - REE) using a biological process as a tool for  solubilization of waste elements with subsequent recovery. The proposed technique is bio-hydrometallurgy, already...
Read more

Importance of technology acceptance assessment for successful implementation and development of new technologies

Introduction It is significant to note that user acceptance and confidence are crucial for further development of any new technology [1,2]. Businesses have facilitated or planning to facilitate their business platform to increase personnel efficiency, marketing improvement, cost reduction and increase profitability. Therefore, recognition the needs and acceptance of individuals is the beginning stage of any businesses and this understanding would be helpful to find the way of future development [3-5]. In general, acceptance is defined as “an antagonism to the term refusal and means the positive decision to use an innovation” [6-8]. Decision makers need to know the issues that influence on users’ decision to use a particular system, so they would be able to take them into account during the development phase [7,8]. Several researches developed theories and models to describe and analyze user acceptance and each of these models determines different factors to explain user acceptance ...
Read more